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Efficient 3D light-sheet imaging of very large-scale optically cleared human brain and prostate tissue samples
oleh: Anna Schueth, Sven Hildebrand, Iryna Samarska, Shubharthi Sengupta, Annemarie Kiessling, Andreas Herrler, Axel zur Hausen, Michael Capalbo, Alard Roebroeck
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
A light-sheet microscopy prototype, the cleared-tissue dual view Selective Plane Illumination Microscope (ct-dSPIM), is presented and shown to enable quantitative assessment of large-scale human tissue samples in 3D with clinical potential.