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The aim of this research was to investigate the age related histomorphological and involutory changes of bursa of Fabricius of sonali chicken at different postnatal stages in Bangladesh. The present research was carried out on bursa of 25 healthy sonali chicken representing different stage of postnatal life; Day 1, Day 14, Day 28, Day 42 and Day 56. Sample (bursa) was collected after sacrificing the chickens by cervical subluxation method. To facilitate microscopic study Harriss Haematoxylin and 1% Eosin Y stain was done. Grossly, the bursa was smooth, yellowish to milkish white in color. The average weight gain, length, width and thickness of bursa was developed parallely with age and found statistically significant (p [ J Adv Biotechnol Exp Ther 2020; 3(1.000): 20-28]