Exploration of the dynamic interplay between lipids and membrane proteins by hydrostatic pressure
oleh: Alexandre Pozza, François Giraud, Quentin Cece, Marina Casiraghi, Elodie Point, Marjorie Damian, Christel Le Bon, Karine Moncoq, Jean-Louis Banères, Ewen Lescop, Laurent J. Catoire
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-04-01 |
Deskripsi
Direct information on the dynamic interplay between membrane proteins and lipids is scarce. Here the authors report a detailed description of these close relationships by combining lipid nanodiscs and high-pressure NMR. They report the link between pressure and lipid compositions to the conformational landscape of the β-barrel OmpX and the α-helical BLT2 G Protein-Coupled Receptor in nanodiscs.