Controlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics
oleh: Xidan Wen, Rui Zhang, Yuxuan Hu, Luyan Wu, He Bai, Dongfan Song, Yanfeng Wang, Ruibing An, Jianhui Weng, Shuren Zhang, Rong Wang, Ling Qiu, Jianguo Lin, Guandao Gao, Hong Liu, Zijian Guo, Deju Ye
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
Manipulating molecular self-assembly and disassembly in vivo may permit temporal control of drug delivery and release. Here, the authors report a fluorogenic cisplatin prodrug for cancer theranostics by leveraging stimuli-triggered in situ self-assembly and intracellular disassembly processes.