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AIM: To evaluate the comfort and visual performance of Rose K2 soft contact lenses in patients with keratoconus.<p>METHODS: Fifty eyes of 50 participants were included in this cross-sectional study. Each participant received a full ophthalmologic examination involving refraction, uncorrected visual acuity(UCVA), best spectacle corrected visual acuity(BCVA), slit-lamp biomicroscopy-fundoscopy, break-up time(BUT), corneal topography, and contrast sensitivity. After contact lens was fitted best contact lens corrected visual acuity(BCLCVA), contrast sensitivity, and comfort rating <i>via</i> visual analogue scales(VAS)were performed.<p>RESULTS: The mean age was 26.2±6.0(range: 16 to 39)y. The mean logMAR UCVA, BCVA, and BCLCVA with Rose K2 soft(in order)were 0.61±0.37(range: 0.15-1.3), 0.42±0.32(range: 0-1.3), and 0.18±0.20(range: 0-1.3). There were significant increases in visual acuities with contact lenses(<i>P</i> < 0.05). The mean contrast sensitivity scores were significantly better with both contact lens in mesopic and photopic conditions(<i>P</i> <0.05). The mean VAS score was 8.02±1.64(range: 5-10)for Rose K2 soft.<p>CONCLUSION: Rose K2 soft contact lens can improve visual acuity, contrast sensitivity with comfort in patients with keratoconus.