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Abstract Under uniaxial compression, a porous rock fails by coalescence of stress‐induced microcracks. The micromechanical models developed to analyze uniaxial compressive strength data consider a single mechanism for the initiation and propagation of microcracks and a fixed starting microstructure. Because the microstructure of clastic porous rock transitions from granular to non‐granular as porosity decreases during diagenesis, their strength cannot be captured by a single model. Using synthetic samples with independently controlled porosity and initial grain radius we show that high‐porosity granular samples, where microcracks grow at grain‐to‐grain contacts, are best described by a grain‐based model. Low‐porosity non‐granular samples, where microcracks grow from pores, are best described by a pore‐based model. The switch from one model to the other depends on porosity and grain radius. We propose a regime plot that indicates which micromechanical model may be more suitable to predict strength for a given porosity and grain radius.