Catalysis of a Bis-Caffeine Palladium(II) NHC-Pincer Complex

oleh: Oliver Bysewski, Andreas Winter, Ulrich S. Schubert

Format: Article
Diterbitkan: MDPI AG 2023-04-01

Deskripsi

A tridentate <i>bis</i>-NHC Pd complex, based on caffeine, was studied for its catalytic activity. This complex displayed a high catalytic activity in the Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions of aryl halides. The Sonogashira cross-coupling was also investigated but reveals a fast plateauing of the reaction. Aryl iodides as well as aryl bromides react when equipped with either electron-donating or electron-withdrawing substituents. Aryl chlorides, which contained electron-withdrawing groups, were also reactive under the applied conditions.