Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

oleh: Michael Taeyoung Hwang, Mohammad Heiranian, Yerim Kim, Seungyong You, Juyoung Leem, Amir Taqieddin, Vahid Faramarzi, Yuhang Jing, Insu Park, Arend M. van der Zande, Sungwoo Nam, Narayana R. Aluru, Rashid Bashir

Format: Article
Diterbitkan: Nature Portfolio 2020-03-01

Deskripsi

Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.