Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart
oleh: Sophie Payne, Mala Gunadasa-Rohling, Alice Neal, Andia N. Redpath, Jyoti Patel, Kira M. Chouliaras, Indrika Ratnayaka, Nicola Smart, Sarah De Val
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-07-01 |
Deskripsi
How coronary vessels develop and respond to injury is not fully understood. Here, the authors use murine enhancer:reporter models to identify three transcriptional pathways active in different parts of coronary vasculature. These also contribute to neovascularization in the injured neonatal, but not adult, heart.