A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
oleh: Yanjun Guo, Pamela M. Rist, Iyas Daghlas, Franco Giulianini, The International Headache Genetics Consortium, The 23andMe Research Team, Tobias Kurth, Daniel I. Chasman
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-07-01 |
Deskripsi
The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.