Assembly intermediates of orthoreovirus captured in the cell
oleh: Geoff Sutton, Dapeng Sun, Xiaofeng Fu, Abhay Kotecha, Corey W. Hecksel, Daniel K. Clare, Peijun Zhang, David I. Stuart, Mark Boyce
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-09-01 |
Deskripsi
Reoviridae undergo a complex assembly pathway in the host cell. Here the authors use cryo-electron tomography to visualize the assembly stages of mammalian orthoreovirus revealing a single shelled intermediate with gross similarity to an early assembly stage of a family of prokaryotic dsRNA viruses.