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Non Hodgkin's lymphoma with cutaneous involvement in AIDS patients. Report of five cases and review of the literature
oleh: Marcelo Corti, Luis De Carolis, Rubén Solari, María F. Villafañe, Ricardo Schtirbu, Daniel Lewi, Marina Narbaitz
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2010-01-01 |
Deskripsi
Cutaneous B cell lymphoma (CBCL) is a lymphoproliferative disorder of neoplastic B cell of the skin with a wide range of clinical manifestations. Commonly, the clinical features of CBCL are plaques, nodules, or ulcerative lesions. Skin is one of the common sites for extra-nodal lymphomas in patients with AIDS and B cell type is less common than T cell type. Only recently, the existence of B cell lymphomas presenting clinically in the skin without evidence of extra-cutaneous involvement has been accepted as primary CBCL. Here, we are presenting 5 patients with cutaneous involvement in the setting of HIV/AIDS disease. Two of them were primary cutaneous non-Hodgkin lymphomas. All were CBCL; 3 were immunoblastic, 1 was plasmablastic, and the other was a Burkitt lymphoma. We analyzed the epidemiological, clinical, virological, and immunological characteristics of this group of patients. Keywords: AIDS, HIV, cutaneous lymphoma