SRC promotes lipogenesis: implications for obesity and breast cancer
oleh: Shu-Yong Lin, Sheng-Cai Lin
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2021-01-01 |
Deskripsi
Remodeling of lipid metabolism has been implicated in cancers; however, it remains obscure how the lipid metabolic pathways are altered by oncogenic signaling to affect tumor development. We have recently shown that proto-oncogene tyrosine-protein kinase Src interacts with and phosphorylates the lipogenesis enzyme phosphatidate phosphatase LPIN1 to promote breast cancer development.