Non-invasive imaging using reporter genes altering cellular water permeability

oleh: Arnab Mukherjee, Di Wu, Hunter C. Davis, Mikhail G. Shapiro

Format: Article
Diterbitkan: Nature Portfolio 2016-12-01

Deskripsi

Magnetic resonance imaging combined with molecular reporters can visualise cellular functions in intact organisms. Here Mukherjeeet al. present a cellular imaging approach based on intracellular changes in water diffusion using human aquaporin 1 gene as a genetically encoded reporter for MRI.