A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations
oleh: Jagjit Singh Bhamra, Per Ole Iversen, Thomas Kjenner Titze, Geir Erland Tjønnfjord, Çiğdem Akalın Akkök
| Format: | Article |
|---|---|
| Diterbitkan: | Hindawi Limited 2018-01-01 |
Deskripsi
Posttransfusion purpura is a serious adverse effect of transfusion due to HPA-antibodies. A young female was diagnosed with acute leukaemia, and treatment commenced. Severe thrombocytopenia ensued. No platelet increment was achieved despite transfusions with buffy coat, HLA-compatible, and HPA-1a negative platelets. The workup indicated the presence of anti-HPA-1a. When the diagnosis of posttransfusion purpura was sufficiently substantiated, she had experienced a fatal intracerebral haemorrhage.