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AIM:To retrospectively evaluate central foveal thickness in highly myopic eyes with best correct visual acuity(BCVA)<or≥0.3 after phacoemulsification(Phaco)using optical coherence tomography(OCT)and to investigate correlation between post-operative BCVA and central foveal thickness. <p>METHODS: In this retrospective clinical study, we consecutively recruited 70 low highly myopic cataract subjects(70 eyes)underwent Phaco. Postoperative visits were performed at 1wk, 1 and 3mo. Postoperative BCVA were recorded and further divided into 2 groups with BCVA< and ≥ than 0.3. Central foveal thickness was measured by OCT 1 and 3mo after surgery. Chi-square test was used to compare preoperative and postoperative BCVA. Pearsion's correlation was used to evaluate relationship between postoperative BCVA and central foveal thickness.<p>RESULTS: The ratio of BCVA<0.05 was 30%,14%, 11% and 7% respectively for per-operation, 1wk, 1 and 3mo post-operation. After surgery, the central foveal thickness was significantly increased in group with BCVA<0.3 comparing to group with BCVA≥0.3. Three month post-operation, central foveal thickness was significantly decreased in both groups comparing to that in 1mo post-operation(<i>P</i><0.01). There has significant correlation between 3mo postoperative BCVA and central foveal thickness(<i>r</i>=-0.716, <i>P</i><0.05).<p>CONCLUSION: In this study, BCVA is improved after 3mo follow up. There has significant correlation between postoperative BCVA and central foveal thickness.