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Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer
oleh: Cam Nguyen, Stephen Leslie, John Gross, Nicholas Dietz, Subodh M. Lele, Gopi Sirineni
Format: | Article |
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Diterbitkan: | Elsevier 2019-11-01 |
Deskripsi
Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology. Keywords: Penile cancer, Anal cancer, Chemotherapy, Radiotherapy, HPV, p16