Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

oleh: Cam Nguyen, Stephen Leslie, John Gross, Nicholas Dietz, Subodh M. Lele, Gopi Sirineni

Format: Article
Diterbitkan: Elsevier 2019-11-01

Deskripsi

Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology. Keywords: Penile cancer, Anal cancer, Chemotherapy, Radiotherapy, HPV, p16