Metaxins are core components of mitochondrial transport adaptor complexes
oleh: Yinsuo Zhao, Eli Song, Wenjuan Wang, Chung-Han Hsieh, Xinnan Wang, Wei Feng, Xiangming Wang, Kang Shen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Mitochondrial trafficking is carefully regulated and functionally important in neurons. Here, the authors screen C. elegans for abnormal mitochondrial distribution and identify metaxin-1 and -2, which bind Miro and microtubule motor proteins to promote mitochondrial trafficking.