Copper-Catalyzed One-Pot Synthesis of <em>N</em>-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides
oleh: Yu Zhao, Zitong Zhou, Man Chen, Weiguang Yang
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-06-01 |
Deskripsi
<i>N</i>-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature. Particularly, the intermediate <i>N</i>-sulfonylketenimines was generated via a CuAAC/ring-opening procedure and took a nucleophilic addition with the weak nucleophile sulfonyl hydrazines. In addition, the stability of the product was tested by a HNMR spectrometer.