Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
oleh: S. Murray Yule, Roderick Skinner, Martin W. English, Mike Cole, Andrew D. J. Pearson, Helen H. Lucraft, Alan W. Craft
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 1998-01-01 |
Deskripsi
Background. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-based regimen with local therapy directed only to children who failed to achieve a complete response to initial chemotherapy.