Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7
oleh: Thomas S. Whittam, Sean D. Reid, Robert K. Selander
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 1998-12-01 |
Deskripsi
It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution.