Hypoxia and the Tumor Microenvironment

oleh: Yue Li MD, Long Zhao, Xiao-Feng Li MD, PhD

Format: Article
Diterbitkan: SAGE Publishing 2021-08-01

Deskripsi

Hypoxia is an important feature of the tumor microenvironment, and is closely associated with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these factors can further promote tumor progression, increase tumor aggressiveness, enhance tumor metastatic potential and lead to poor prognosis. In this review, these effects of hypoxia on tumor biology will be discussed, along with their significance for tumor detection and treatment.