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The harmful nature of high concentrations of antibiotics to humans and animals requires the urgent development of novel materials and techniques for their absorption. In this work, CTAB (Cetyltrimethyl Ammonium Bromide)-assisted synthesis of ZIF-8 (zeolitic imidazolate framework)-derived hollow carbon (ZHC) was designed, prepared, and used as a high-performance adsorbent, and further evaluated by Langmuir and Freundlich isothermal adsorption experiments, dynamic analysis, as well as theoretical calculation. The maximum capacities of ZHC for adsorbing tetracycline (TC), norfloxacin (NFO), and levofloxacin (OFO) are 267.3, 125.6, and 227.8 mg g-1, respectively, which delivers superior adsorptive performance when compared to widely studied inorganic adsorbates. The design concept of ZIF-8-derived hollow carbon material provides guidance and insights for the efficient adsorbent of environmental antibiotics.