IL-1-dependent enteric gliosis guides intestinal inflammation and dysmotility and modulates macrophage function

oleh: Reiner Schneider, Patrick Leven, Shilpashree Mallesh, Mona Breßer, Linda Schneider, Elvio Mazzotta, Paola Fadda, Tim Glowka, Tim O. Vilz, Philipp Lingohr, Jörg C. Kalff, Fievos L. Christofi, Sven Wehner

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

IL1R1-signaling triggers enteric glia reactivity, resulting in enteric gliosis, macrophage activation and the development of postoperative ileus.