The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway
oleh: Guoguo Wan, Zhiwei Chen, Lei Lei, Xiaoyu Geng, Yi Zhang, Congwen Yang, Wenfu Cao, Zheng Pan
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2023-02-01 |
Deskripsi
Highlights Chemical composition of TPRL was identified by UPLC-Q/TOF/MSn in the profile of total ion current. TPRL was initially demostrated the effects of anti-hepatic fibrosis in vitro and in vivo. TPRL ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.