Self-organized centripetal movement of corneal epithelium in the absence of external cues

oleh: Erwin P. Lobo, Naomi C. Delic, Alex Richardson, Vanisri Raviraj, Gary M. Halliday, Nick Di Girolamo, Mary R. Myerscough, J. Guy Lyons

Format: Article
Diterbitkan: Nature Portfolio 2016-08-01

Deskripsi

The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.