Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
oleh: Olga Snitser, Dor Russ, Laura K. Stone, Kathy K. Wang, Haleli Sharir, Noga Kozer, Galit Cohen, Haim M. Barr, Roy Kishony
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-11-01 |
Deskripsi
The mecA gene confers resistance to many β-lactam antibiotics in community-associated MRSA bacteria. Here, Snitser et al. show that mecA also provides broad selective advantage across diverse chemical environments in the presence of subinhibitory β-lactam concentrations, by protecting the bacteria against increased cell-envelope permeability.