Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
oleh: Jonathan Latham, Jean-Marc Henry, Humera H. Sharif, Binuraj R. K. Menon, Sarah A. Shepherd, Michael F. Greaney, Jason Micklefield
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-06-01 |
Deskripsi
Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the two chemistries.