A lipid gating mechanism for the channel-forming O antigen ABC transporter

oleh: Christopher A. Caffalette, Robin A. Corey, Mark S. P. Sansom, Phillip J. Stansfeld, Jochen Zimmer

Format: Article
Diterbitkan: Nature Portfolio 2019-02-01

Deskripsi

Bacterial O antigen polysaccharides play a role in innate immune response evasion. Here, the authors uncover the ATP-bound structure of the Aquifex aeolicus WzmWzt O antigen ABC transporter, shedding light onto the mechanism of lipid-linked polysaccharide translocation.