Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults
oleh: Zachary K. Sagawa, Cristina Goman, Aude Frevol, Azra Blazevic, Janice Tennant, Bridget Fisher, Tracey Day, Stephen Jackson, Franck Lemiale, Leon Toussaint, Irene Kalisz, Joe Jiang, Lisa Ondrejcek, Raodoh Mohamath, Julie Vergara, Alan Lew, Anna Marie Beckmann, Corey Casper, Daniel F. Hoft, Christopher B. Fox
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Here the authors present results from a randomized, double-blinded Phase 1 clinical trial, testing a thermostable presentation of a clinical-stage adjuvanted subunit tuberculosis vaccine candidate. The vaccine candidate is safe and well tolerated, and elicits comparable or improved immune responses compared to the non-thermostable presentation.