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Wood processing is a crucial step of wood utilization, but the adding of environmentally hazardous feedstocks and the use of unreasonable technology allow it to harm the environment and human health. Supercritical CO₂ (scCO₂) is a non-toxic, odorless, and safe solvent, which is widely used in studies and industrial production, but there is no review summarizing wood processing with scCO₂. The unique structure and chemical properties of wood combined with scCO₂ technology produce positive results. In this paper, wood processing with scCO₂ is summarized, including wood impregnation, wood drying, wood thermochemical conversion, and wood extraction. The green and efficient characteristics of wood processing with scCO₂ are explained in detail for researchers, engineers, and investors to provide a clean wood processing method. Further study is needed to reduce its energy consumption and commercialize it eventually.