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With a new therapy of keratoconus in recent years-corneal cross-linking, the pediatric keratoconus have characterized by corneal dilatation, central thinning, protrusion and conical shape in the children' eyes. By analyzing the epidemiological characteristics of keratoconus and the current methods of treating pediatric keratcoconus, this paper discusses the role of different CXL protocols in the clinical application of pediatric keratcoconus, thus providing some help for the choice of clinical treatment methods.