An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases

oleh: Ondřej Gahura, Alexander Mühleip, Carolina Hierro-Yap, Brian Panicucci, Minal Jain, David Hollaus, Martina Slapničková, Alena Zíková, Alexey Amunts

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

Mitochondrial ATP synthase assemble into oligomers. Here, authors resolve the structure of trypanosomal ATP synthase, showing that its dimerization is essential for function and evolutionary conserved.