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Primed histone demethylation regulates shoot regenerative competency
oleh: Hiroya Ishihara, Kaoru Sugimoto, Paul T. Tarr, Haruka Temman, Satoshi Kadokura, Yayoi Inui, Takuya Sakamoto, Taku Sasaki, Mitsuhiro Aida, Takamasa Suzuki, Soichi Inagaki, Kengo Morohashi, Motoaki Seki, Tetsuji Kakutani, Elliot M. Meyerowitz, Sachihiro Matsunaga
Format: | Article |
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Diterbitkan: | Nature Portfolio 2019-04-01 |
Deskripsi
Plant regeneration can occur via formation of a mass of pluripotent cells known as callus. Here, Ishihara et al. show that acquisition of regenerative capacity of callus-forming cells requires a lysine-specific demethylase that removes H3K4me2 to prime gene expression in response to regenerative cues.