Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation

oleh: Matthew Jessop, Karine Huard, Ambroise Desfosses, Guillaume Tetreau, Diego Carriel, Maria Bacia-Verloop, Caroline Mas, Philippe Mas, Angélique Fraudeau, Jacques-Philippe Colletier, Irina Gutsche

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

Jessop et. al. investigate the expression, activity, structure and supramolecular assembly of the arginine decarboxylase from Providencia stuartii, compare its polymers with those formed by the Escherichia coli lysine decarboxylase, and analyse the evolutionary conservation of the structural determinants of the polymerisation of these enzymes in enterobacteria.