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Objective: To determine the frequency of undiagnosed hypothyroidism in obese females. Study Design: Descriptive cross sectional study. Place and Duration of Study: Combined Military Hospital Peshawar, from Aug 2015 to Dec 2015. Methodology: All individuals who were fulfilling the inclusion criteria were considered in the study after informed consent. The body mass index was calculated and their blood drawn for biochemical results. All the data was entered in SPSS-20 and results obtained. Results: All participants were females, and their mean age (± SD) was 46.78 (± 11.272) years. The overall frequency of undiagnosed hypothyroidism was 5% (6 out of the 130 subjects). Conclusion: Although, there is obvious linkage between (TSH) thyroid stimulating hormone and degree of obesity, however, the determined results/frequency of hypothyroidism in obese females are not high enough to recommend large scale/mass screening.