Measuring macromolecular size distributions and interactions at high concentrations by sedimentation velocity
oleh: Sumit K. Chaturvedi, Jia Ma, Patrick H. Brown, Huaying Zhao, P. Schuck
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-10-01 |
Deskripsi
Many aspects of concentrated macromolecular solutions, such as encountered in cytosol or in pharmaceutical formulations, are dependent on particle size distributions and weak intermolecular interactions. Here, the authors exploit hydrodynamic separation in the centrifugal field to measure both.