MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
oleh: Jakub Mieczkowski, April Cook, Sarah K. Bowman, Britta Mueller, Burak H. Alver, Sharmistha Kundu, Aimee M. Deaton, Jennifer A. Urban, Erica Larschan, Peter J. Park, Robert E. Kingston, Michael Y. Tolstorukov
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-05-01 |
Deskripsi
Nucleosome positioning and chromatin accessibility are important contributors to the regulation of gene expression. Here the authors describe a method that allows the simultaneous measurement of nucleosome occupancy and chromatin accessibility in the same assay, revealing new features of chromatin organization linked to gene regulation.