Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host
oleh: Sissy Therese Sonnleitner, Martina Prelog, Stefanie Sonnleitner, Eva Hinterbichler, Hannah Halbfurter, Dominik B. C. Kopecky, Giovanni Almanzar, Stephan Koblmüller, Christian Sturmbauer, Leonard Feist, Ralf Horres, Wilfried Posch, Gernot Walder
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
Variants of concerns arise from SARS-CoV-2 mutations poise as severe public health threats. Here the authors chronicle SARS-CoV-2 mutations onset and immune parameters in an immunocompromised patient with continuous virus-shedding, thereby hinting potential intra-host viral evolution and escape facilitated by ineffective T cell immunity.