Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines

oleh: Derek R. Stein, Patrycja Sroga, Bryce M. Warner, Yvon Deschambault, Guillaume Poliquin, David Safronetz

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2019-08-01

Deskripsi

Use of the vesicular stomatitis virus (VSV)–based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines’ stability should the cold chain fail. We demonstrated that current cold chain conditions might tolerate significant variances without affecting efficacy.