The extracellular matrix regulates cortical layer dynamics and cross-columnar frequency integration in the auditory cortex

oleh: Mohamed El-Tabbal, Hartmut Niekisch, Julia U. Henschke, Eike Budinger, Renato Frischknecht, Matthias Deliano, Max F. K. Happel

Format: Article
Diterbitkan: Nature Portfolio 2021-03-01

Deskripsi

El-Tabbal et al removed the extracellular matrix (ECM) in the primary auditory cortex of Mongolian gerbils and assessed both spontaneous and elicited neural activity. They show that ECM degradation alters translaminar cortical network dynamics and they consider its role in neural plasticity.