Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels
oleh: Martina Rangl, Atsushi Miyagi, Julia Kowal, Henning Stahlberg, Crina M. Nimigean, Simon Scheuring
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-09-01 |
Deskripsi
Some ion channels are modulated by binding of cyclic nucleotide to a cyclic nucleotide-binding domain. Here, the authors use high-speed atomic force microscopy to directly monitor the conformational changes induced by ligand binding to a cyclic nucleotide-modulated channel from Mesorhizobium loti.