Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner
oleh: Tehasi Wang, Chengguang Zhang, Shuren Wang
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2021-12-01 |
Deskripsi
Highlights 1. Circ_0003074 expression was upregulated in OS tissues and cells. 2. Rg3 treatment significantly decreased circ_0003074 expression in OS cells. 3. Circ_0003074 overexpression rescued Rg3-induced inhibition in OS progression. 4. Circ_0003074 induced KPNA4 production through miR-516b-5p under Rg3 treatment.