Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure
oleh: Chih-Yang Huang, Chia-Hua Kuo, Pei-Ying Pai, Tsung-Jung Ho, Yueh-Min Lin, Ray-Jade Chen, Fuu-Jen Tsai, V. Vijaya Padma, Wei-Wen Kuo, Chih-Yang Huang
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2018-02-01 |
Deskripsi
In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.