An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins

oleh: Haopeng Xiao, Weixuan Chen, Johanna M. Smeekens, Ronghu Wu

Format: Article
Diterbitkan: Nature Portfolio 2018-04-01

Deskripsi

Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichment, providing the basis for more comprehensive glycoprotein analyses.