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An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins
oleh: Haopeng Xiao, Weixuan Chen, Johanna M. Smeekens, Ronghu Wu
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-04-01 |
Deskripsi
Understanding the functions of protein glycosylation critically depends on methods to efficiently enrich glycoproteins from complex samples. Here, the authors develop a strategy using dendrimer-conjugated benzoboroxole to enhance glycopeptide enrichment, providing the basis for more comprehensive glycoprotein analyses.