The effect of a loading dose of meropenem on outcomes of patients with sepsis treated by continuous renal replacement: study protocol for a randomized controlled trial oleh Sui-Qing Ni, Wen-Bing Teng, Yong-Hong Fu, Wei Su, Zhi Yang, Jie Cai, Jin-Nuo Xu, Xiao-Ying Deng, Xiang-Fang Liu, Sheng-Nan Fu, Jun Zeng, Chen Zhang