Hasil Pencarian - Yaogeng Wang

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  1. 1
    P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO)

    P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO) oleh Yaogeng Wang, Rolf W. Sparidans, Sander Potters, Rahime Şentürk, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2021-10-01
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  2. 2
    Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c

    Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c oleh Nancy H.C. Loos, Irene A. Retmana, Jamie Rijmers, Yaogeng Wang, Changpei Gan, Maria C. Lebre, Rolf W. Sparidans, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2023-10-01
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  3. 3
    Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs

    Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs oleh Wenlong Li, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Yaogeng Wang, Dirk R. de Waart, Margarida L.F. Martins, Stéphanie van Hoppe, Maria C. Lebre, Olaf van Tellingen, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2023-04-01
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  4. 4
    Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs

    Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs oleh Wenlong Li, Rolf W. Sparidans, Yaogeng Wang, Margarida L.F. Martins, Dirk R. de Waart, Olaf van Tellingen, Ji-Ying Song, Maria C. Lebre, Stéphanie van Hoppe, Els Wagenaar, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2024-06-01
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  5. 5
    Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism

    Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism oleh Changpei Gan, Jing Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Els Wagenaar, Yaogeng Wang, Maria C. Lebre, Hilde Rosing, Sjoerd Klarenbeek, Rahmen Bin Ali, Colin Pritchard, Ivo Huijbers, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2023-02-01
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  6. 6
    Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development

    Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development oleh Changpei Gan, Jing Wang, Yaogeng Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Maria C. Lebre, Els Wagenaar, Hilde Rosing, Sjoerd Klarenbeek, Onno B. Bleijerveld, Ji-Ying Song, Maarten Altelaar, Jos H. Beijnen, Alfred H. Schinkel

    Diterbitkan 2023-08-01
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