Search Results - Wolfgang Sippl

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  1. 1
    Editorial for Special Issue—“Early-Stage Drug Discovery: Advances and Challenges”

    Editorial for Special Issue—“Early-Stage Drug Discovery: Advances and Challenges” by Wolfgang Sippl

    Published 2023-03-01
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  2. 2
    Histone Acetyltransferase and Deacetylase Inhibitors—New Aspects and Developments

    Histone Acetyltransferase and Deacetylase Inhibitors—New Aspects and Developments by Hany S. Ibrahim, Wolfgang Sippl

    Published 2023-11-01
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  3. 3
    Editorial to Special Issue—“Structure-Activity Relationships (SAR) of Natural Products”

    Editorial to Special Issue—“Structure-Activity Relationships (SAR) of Natural Products” by Wolfgang Sippl, Fidele Ntie-Kang

    Published 2021-01-01
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  4. 4
    Editorial: Application of PROTACs as a Novel Strategy for Drug Discovery

    Editorial: Application of PROTACs as a Novel Strategy for Drug Discovery by Hany S. Ibrahim, Hany S. Ibrahim, Wolfgang Sippl

    Published 2021-07-01
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  5. 5
    Natural Products as Modulators of Sirtuins

    Natural Products as Modulators of Sirtuins by Berin Karaman Mayack, Wolfgang Sippl, Fidele Ntie-Kang

    Published 2020-07-01
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  6. 6
    <i>N</i><sup>4</sup>-(2-Amino-4-fluorophenyl)-<i>N</i><sup>1</sup>-(3-{2-[2-(3-{[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino}propoxy)ethoxy]ethoxy}propyl)terephthalamide

    <i>N</i><sup>4</sup>-(2-Amino-4-fluorophenyl)-<i>N</i><sup>1</sup>-(3-{2-[2-(3-{[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino}propoxy)ethoxy]ethoxy}propyl)terephthalami... by Mohamed Abdelsalam, Matthes Zessin, Matthias Schmidt, Mike Schutkowski, Wolfgang Sippl

    Published 2022-11-01
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  7. 7
    Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis

    Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis by Conrad V. Simoben, Fidele Ntie-Kang, Sergi H. Akone, Wolfgang Sippl

    Published 2018-05-01
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  8. 8
    Pharmacogenetic Aspects of the Interaction of AT1 Receptor Antagonists With ATP-Binding Cassette Transporter ABCG2

    Pharmacogenetic Aspects of the Interaction of AT1 Receptor Antagonists With ATP-Binding Cassette Transporter ABCG2 by Anne Ripperger, Anna Krischer, Dina Robaa, Wolfgang Sippl, Ralf A. Benndorf

    Published 2018-05-01
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  9. 9
    Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition

    Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition by Kristina King, Alexander-Thomas Hauser, Jelena Melesina, Wolfgang Sippl, Manfred Jung

    Published 2018-02-01
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  10. 10
    Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis

    Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis by Ehab Ghazy, Mohamed Abdelsalam, Dina Robaa, Raymond J. Pierce, Wolfgang Sippl

    Published 2022-01-01
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  11. 11
    Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.

    Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. by Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker

    Published 2015-01-01
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  12. 12
    Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor

    Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor by Fady Baselious, Sebastian Hilscher, Dina Robaa, Cyril Barinka, Mike Schutkowski, Wolfgang Sippl

    Published 2024-01-01
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  13. 13
    Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

    Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites by Ming Jang Chua, Dina Robaa, Tina S. Skinner-Adams, Wolfgang Sippl, Katherine T. Andrews

    Published 2018-08-01
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  14. 14
    Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases

    Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases by Matthias Schmidt, Alexander Rohe, Charlott Platzer, Abdulkarim Najjar, Frank Erdmann, Wolfgang Sippl

    Published 2017-11-01
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  15. 15
    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R

    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R by Cornelius Hempel, Frank Totzke, Christoph Schächtele, Abdulkarim Najjar, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

    Published 2017-01-01
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  16. 16
    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance

    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance by Tim Fischer, Abdulkarim Najjar, Frank Totzke, Christoph Schächtele, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

    Published 2018-01-01
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  17. 17
    2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity.

    2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity. by Lei Wang, Marina Kofler, Gerald Brosch, Jelena Melesina, Wolfgang Sippl, Elisabeth D Martinez, Johnny Easmon

    Published 2015-01-01
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  18. 18
    How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

    How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine by Anne Wurzlbauer, Katharina Rüben, Ece Gürdal, Apirat Chaikuad, Stefan Knapp, Wolfgang Sippl, Walter Becker, Franz Bracher

    Published 2020-12-01
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  19. 19
    Application of Ligand- and Structure-Based Prediction Models for the Design of Alkylhydrazide-Based HDAC3 Inhibitors as Novel Anti-Cancer Compounds

    Application of Ligand- and Structure-Based Prediction Models for the Design of Alkylhydrazide-Based HDAC3 Inhibitors as Novel Anti-Cancer Compounds by Emre F. Bülbül, Dina Robaa, Ping Sun, Fereshteh Mahmoudi, Jelena Melesina, Matthes Zessin, Mike Schutkowski, Wolfgang Sippl

    Published 2023-07-01
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  20. 20
    Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of <i>Schistosoma mansoni</i> Histone Deacetylase 8 (<i>sm</i>HDAC8) Inhibitors

    Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of <i>Schistosoma mansoni</i> Histone Deacetylase 8 (<i>sm</i>HDAC8) Inhibit... by Conrad V. Simoben, Ehab Ghazy, Patrik Zeyen, Salma Darwish, Matthias Schmidt, Christophe Romier, Dina Robaa, Wolfgang Sippl

    Published 2021-04-01
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