Hasil Pencarian - Timothy Palzkill

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  1. 1
    Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases

    Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases oleh Timothy Palzkill, Timothy Palzkill

    Diterbitkan 2018-02-01
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  2. 2
    Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1

    Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1 oleh Zhizeng Sun, Timothy Palzkill

    Diterbitkan 2021-12-01
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  3. 3
    Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability.

    Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability. oleh Shrenik C Mehta, Kacie Rice, Timothy Palzkill

    Diterbitkan 2015-06-01
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  4. 4
    How structural and physicochemical determinants shape sequence constraints in a functional enzyme.

    How structural and physicochemical determinants shape sequence constraints in a functional enzyme. oleh Luciano A Abriata, Timothy Palzkill, Matteo Dal Peraro

    Diterbitkan 2015-01-01
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  5. 5
    Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics

    Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics oleh Zhizeng Sun, Liya Hu, Banumathi Sankaran, B. V. Venkataram Prasad, Timothy Palzkill

    Diterbitkan 2018-10-01
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  6. 6
    Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Clinical Isolates

    Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from <named-content content-type="genus-species">Klebsiella pneumoniae</named-c... oleh Shuo Lu, Victoria Soeung, Hoang A. T. Nguyen, S. Wesley Long, James M. Musser, Timothy Palzkill

    Diterbitkan 2020-02-01
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  7. 7
    Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response

    Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response oleh Lynn Su, Wanzhi Huang, Frederick H. Neill, Mary K. Estes, Robert L. Atmar, Timothy Palzkill

    Diterbitkan 2023-06-01
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  8. 8
    Identification and Characterization of Single-Chain Antibodies that Specifically Bind GI Noroviruses.

    Identification and Characterization of Single-Chain Antibodies that Specifically Bind GI Noroviruses. oleh Amy M Hurwitz, Wanzhi Huang, Baijun Kou, Mary K Estes, Robert L Atmar, Timothy Palzkill

    Diterbitkan 2017-01-01
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  9. 9
    Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase

    Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase oleh Allison Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B. V. Venkataram Prasad, Timothy Palzkill

    Diterbitkan 2023-01-01
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  10. 10
    The binary protein interactome of Treponema pallidum--the syphilis spirochete.

    The binary protein interactome of Treponema pallidum--the syphilis spirochete. oleh Björn Titz, Seesandra V Rajagopala, Johannes Goll, Roman Häuser, Matthew T McKevitt, Timothy Palzkill, Peter Uetz

    Diterbitkan 2008-05-01
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  11. 11
    Physiological roles of ArcA, Crp, and EtrA and their interactive control on aerobic and anaerobic respiration in Shewanella oneidensis.

    Physiological roles of ArcA, Crp, and EtrA and their interactive control on aerobic and anaerobic respiration in Shewanella oneidensis. oleh Haichun Gao, Xiaohu Wang, Zamin K Yang, Jingrong Chen, Yili Liang, Haijiang Chen, Timothy Palzkill, Jizhong Zhou

    Diterbitkan 2010-01-01
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  12. 12
    An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes

    An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes oleh Shuo Lu, Liya Hu, Hanfeng Lin, Allison Judge, Paola Rivera, Murugesan Palaniappan, Banumathi Sankaran, Jin Wang, B. V. Venkataram Prasad, Timothy Palzkill

    Diterbitkan 2022-11-01
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  13. 13
    Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor.

    Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor. oleh Fei Yan, Yang Yu, Dar-Chone Chow, Timothy Palzkill, Franck Madoux, Peter Hodder, Peter Chase, Patrick R Griffin, Bert W O'Malley, David M Lonard

    Diterbitkan 2014-01-01
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  14. 14
    Generation and validation of a Shewanella oneidensis MR-1 clone set for protein expression and phage display.

    Generation and validation of a Shewanella oneidensis MR-1 clone set for protein expression and phage display. oleh Haichun Gao, Donna Pattison, Tingfen Yan, Dawn M Klingeman, Xiaohu Wang, Joseph Petrosino, Lisa Hemphill, Xiufeng Wan, Adam B Leaphart, George M Weinstock, Timothy Palzkill, Jizhong Zhou

    Diterbitkan 2008-01-01
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  15. 15
    Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding.

    Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. oleh Jeong Joo Kim, Darren E Casteel, Gilbert Huang, Taek Hun Kwon, Ronnie Kuo Ren, Peter Zwart, Jeffrey J Headd, Nicholas Gene Brown, Dar-Chone Chow, Timothy Palzkill, Choel Kim

    Diterbitkan 2011-04-01
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  16. 16
    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters oleh Margie N. Sutton, Zhen Lu, Yao-Cheng Li, Yong Zhou, Tao Huang, Albert S. Reger, Amy M. Hurwitz, Timothy Palzkill, Craig Logsdon, Xiaowen Liang, Joe W. Gray, Xiaolin Nan, John Hancock, Geoffrey M. Wahl, Robert C. Bast, Jr.

    Diterbitkan 2019-12-01
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  17. 17
    DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors

    DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors oleh Ravikumar Jimmidi, Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Peng-Jen Chen, Kurt M. Bohren, Seyed Arad Moghadasi, Leroy Versteeg, Christina Nnabuife, Jian-Yuan Li, Xuan Qin, Ying-Chu Chen, John C. Faver, Pranavanand Nyshadham, Kiran L. Sharma, Banumathi Sankaran, Allison Judge, Zhifeng Yu, Feng Li, Jeroen Pollet, Reuben S. Harris, Martin M. Matzuk, Timothy Palzkill, Damian W. Young

    Diterbitkan 2023-08-01
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