Hasil Pencarian - Timothy M. Frayling
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Mendelian Randomization Analyses Suggest Childhood Body Size Indirectly Influences End Points From Across the Cardiovascular Disease Spectrum Through Adult Body Size oleh Grace M. Power, Jessica Tyrrell, Timothy M. Frayling, George Davey Smith, Tom G. Richardson
Diterbitkan 2021-09-01Dapatkan teks lengkap
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Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes. oleh Bahram Jafar-Mohammadi, Christopher J Groves, Katharine R Owen, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Anna L Gloyn
Diterbitkan 2009-08-01Dapatkan teks lengkap
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Quantification of the overall contribution of gene-environment interaction for obesity-related traits oleh Jonathan Sulc, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R. Wood, Timothy M. Frayling, Iris M. Heid, Matthew R. Robinson, Zoltán Kutalik
Diterbitkan 2020-03-01Dapatkan teks lengkap
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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. oleh Harry D Green, Alistair Jones, Jonathan P Evans, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Christopher Smith, Michael N Weedon
Diterbitkan 2021-06-01Dapatkan teks lengkap
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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor oleh Harry D. Green, Alistair Jones, Jonathan P. Evans, Andrew R. Wood, Robin N. Beaumont, Jessica Tyrrell, Timothy M. Frayling, Christopher Smith, Michael N. Weedon
Diterbitkan 2021-06-01Dapatkan teks lengkap
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Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable. oleh Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, George Davey Smith
Diterbitkan 2008-03-01Dapatkan teks lengkap
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8
Identification and analysis of individuals who deviate from their genetically-predicted phenotype. oleh Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood
Diterbitkan 2023-09-01Dapatkan teks lengkap
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9
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. oleh Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling
Diterbitkan 2006-10-01Dapatkan teks lengkap
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10
Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records oleh Katherine S. Ruth, Robin N. Beaumont, Jonathan M. Locke, Jessica Tyrrell, Carolyn J. Crandall, Gareth Hawkes, Timothy M. Frayling, Julia K. Prague, Kashyap A. Patel, Andrew R. Wood, Michael N. Weedon, Anna Murray
Diterbitkan 2023-10-01Dapatkan teks lengkap
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Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. oleh Neelam Hassanali, N Maneka G De Silva, Neil Robertson, N William Rayner, Amy Barrett, Amanda J Bennett, Christopher J Groves, David R Matthews, Prasad Katulanda, Timothy M Frayling, Mark I McCarthy
Diterbitkan 2014-01-01Dapatkan teks lengkap
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12
Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis oleh Emma Hazelwood, Eleanor Sanderson, Vanessa Y. Tan, Katherine S. Ruth, Timothy M. Frayling, Niki Dimou, Marc J. Gunter, Laure Dossus, Claire Newton, Neil Ryan, Dimitri J. Pournaras, Tracy A. O’Mara, George Davey Smith, Richard M. Martin, James Yarmolinsky
Diterbitkan 2022-04-01Dapatkan teks lengkap
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Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals. oleh Yingleong Chan, Oddgeir L Holmen, Andrew Dauber, Lars Vatten, Aki S Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang T Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M Frayling, Joel N Hirschhorn, Michael N Weedon
Diterbitkan 2011-12-01Dapatkan teks lengkap
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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... oleh Andrew R Wood, John R B Perry, Toshiko Tanaka, Dena G Hernandez, Hou-Feng Zheng, David Melzer, J Raphael Gibbs, Michael A Nalls, Michael N Weedon, Tim D Spector, J Brent Richards, Stefania Bandinelli, Luigi Ferrucci, Andrew B Singleton, Timothy M Frayling
Diterbitkan 2013-01-01Dapatkan teks lengkap
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The impact of Mendelian sleep and circadian genetic variants in a population setting. oleh Michael N Weedon, Samuel E Jones, Jacqueline M Lane, Jiwon Lee, Hanna M Ollila, Amy Dawes, Jess Tyrrell, Robin N Beaumont, Timo Partonen, Ilona Merikanto, Stephen S Rich, Jerome I Rotter, Timothy M Frayling, Martin K Rutter, Susan Redline, Tamar Sofer, Richa Saxena, Andrew R Wood
Diterbitkan 2022-09-01Dapatkan teks lengkap
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Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits. oleh Craig A Glastonbury, Sara L Pulit, Julius Honecker, Jenny C Censin, Samantha Laber, Hanieh Yaghootkar, Nilufer Rahmioglu, Emilie Pastel, Katerina Kos, Andrew Pitt, Michelle Hudson, Christoffer Nellåker, Nicola L Beer, Hans Hauner, Christian M Becker, Krina T Zondervan, Timothy M Frayling, Melina Claussnitzer, Cecilia M Lindgren
Diterbitkan 2020-08-01Dapatkan teks lengkap
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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. oleh Luke C Pilling, Janice L Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer
Diterbitkan 2017-01-01Dapatkan teks lengkap
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Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives oleh Tom G Richardson, PhD, Qin Wang, PhD, Eleanor Sanderson, PhD, Anubha Mahajan, PhD, Mark I McCarthy, ProfMD, Timothy M Frayling, ProfPhD, Mika Ala-Korpela, ProfPhD, Allan Sniderman, ProfMD, George Davey Smith, ProfFRS, Michael V Holmes, MD
Diterbitkan 2021-06-01Dapatkan teks lengkap
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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. oleh Christopher G Bell, Sarah Finer, Cecilia M Lindgren, Gareth A Wilson, Vardhman K Rakyan, Andrew E Teschendorff, Pelin Akan, Elia Stupka, Thomas A Down, Inga Prokopenko, Ian M Morison, Jonathan Mill, Ruth Pidsley, International Type 2 Diabetes 1q Consortium, Panos Deloukas, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Stephan Beck, Graham A Hitman
Diterbitkan 2010-11-01Dapatkan teks lengkap
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The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study oleh Junxi Liu, Rebecca C. Richmond, Emma L. Anderson, Jack Bowden, Ciarrah-Jane S. Barry, Hassan S. Dashti, Iyas S. Daghlas, Jacqueline M. Lane, Simon D. Kyle, Céline Vetter, Claire L. Morrison, Samuel E. Jones, Andrew R. Wood, Timothy M. Frayling, Alison K. Wright, Matthew J. Carr, Simon G. Anderson, Richard A. Emsley, David W. Ray, Michael N. Weedon, Richa Saxena, Martin K. Rutter, Deborah A. Lawlor
Diterbitkan 2024-06-01Dapatkan teks lengkap
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